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Search Results for " orally active "

20

Compounds

Cat No. Product Name Synonyms Targets
T8348 Phentolamine Adrenergic Receptor
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist
T8580 Bupranolol Adrenergic Receptor
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
T9565 OSBPL7-IN-1 Others
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].
T9732 VY-3-135 Fatty Acid Synthase
VY-3-135 is a metastasis inhibitor and an acetyl-CoA synthetase 2 (ACSS2) modulator.
T1292 Tiapride hydrochloride Dopamine Receptor
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw...
T8734 Choline Others
Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins
T34896 Tofisopam Emandaxin,Grandaxin Others
Tofisopam (Grandaxin) is a 2,3-benzodiazepine compound with anxiolytic activity that can be taken orally.
T9805 BAY 2666605 PDE
BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.
T9164 BMS-986242 BMS986242 IDO , Indoleamine 2,3-Dioxygenase (IDO)
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.
T9590 T-1095 SGLT , transporter
T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).
T2629 UNC2881 TAM Receptor
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.
T9977 SGK1-IN-4 SGK
SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.
T7686 Ramiprilat RAAS
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T8581 Flecainide hydrochloride Others
Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.
T36670 JNJ-67856633 MALT
JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease . JNJ-67856633 lead to tumor stasis in some cases.
T17158 Trans-AUCB t-AUCB Epoxide Hydrolase
trans-AUCB (t-AUCB) is an effective and selective soluble epoxide hydrolase inhibitor (IC50s: 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively).
T2678 LB42708 Transferase
LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).
T22304 Desciclovir BW A515U,6-Deoxyacyclovir,DCV Antifection
Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.
T3858 Macranthoidin A Others
Macranthoidin A has anti-inflammation activity.
T4S1114 Dryocrassin ABBA Dryocrassin Influenza Virus , Antibacterial
Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities.
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